Web22 nov. 2024 · [ASAP] Meroantarctines A –C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus < italic toggle="yes" > Penicillium antarcticum < /italic > KMM 4685 with Potent p ‑Glycoprotein Inhibitory Activity WebMeroantarctines A-C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity.
Meroantarctines A-C, Meroterpenoids with Rearranged Skeletons …
WebMeroantarctines A-C (1-3) inhibited p-glycoprotein activity and could resensitize drug-resistant cancer cells to docetaxel. AB - New meroterpenoids, meroantarctines A-C (1-3), with unique 6/5/6/6, 6/5/6/5/6, and 6/5/6/5 polycyclic systems were isolated from the alga … Web22 nov. 2024 · Their structures were elucidated by spectroscopic methods, X-ray diffraction, and quantum chemical calculations. A biogenetic pathway for 1-3 was proposed. Meroantarctines A-C (1-3) inhibited p-glycoprotein activity and could resensitize drug … galling and seizing
Sergey DYSHLOVOY PostDoc Priv.-Doz; PhD; DSc - ResearchGate
Web22 nov. 2024 · Meroantarctines A–C, Meroterpenoids with Rearranged Skeletons from the Alga-Derived Fungus Penicillium antarcticum KMM 4685 with Potent p-Glycoprotein Inhibitory Activity Request PDF. WebFive new β-resorcylic acid derivatives isolated from the ethyl acetate extract of the fungus Penicillium antarcticum KMM 4685 associated with the brown alga Sargassum miyabei exhibited moderate cytotoxic activity in LNCaP, DU145 and 22Rv1 human prostate cancer cells and could inhibit the activity of p-glycoprotein at their noncytotoxic concentrations. … Web14 mrt. 2024 · Recently, our group reported the isolation and characterization of three new bioactive meroterpenoids with rearranged skeletons, meroantarctines A–C, from the Penicillium antarcticum KMM 4685 . Further searches for of new metabolites from this fungus strain resulted in the isolation of six β-resorcylic acid derivatives ( 1 – 6 ) ( Figure 1 ). blackcat paintball