Mitotic somal translocation
WebWe highlight how gene expression studies have identified molecular signatures for radial glial cell populations and outline what has been learned about the mechanisms underlying the characteristic mode of division observed in … Web20 aug. 2024 · They display a highly specific cytokinesis behavior termed mitotic somal translocation. We focus here on recently identified molecular mechanisms associated with the generation and amplification of bRGs, including bRG-like cells in the rodent.
Mitotic somal translocation
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WebEvolutionary expansion of the human neocortex is partially attributed to a relative abundance of neural stem cells in the fetal brain called outer radial glia (oRG). oRG cells display a characteristic division mode, mitotic somal translocation (MST), in which the soma rapidly translocates toward the cortical plate immediately prior to cytokinesis. Web2 sep. 2024 · In particular, oRG cells, a predominant progenitor population in the developing human cortex, contribute extensively to cortical expansion and folding due, in part, to …
WebUsing live time-lapse imaging of primary resected tumors, we discover that tumor-derived oRG-like cells undergo characteristic mitotic somal translocation behavior previously … WebNational Center for Biotechnology Information
Web12 dec. 2016 · Search worldwide, life-sciences literature Search. Advanced Search Coronavirus articles and preprints Search examples: "breast cancer" Smith J"breast … Web1 feb. 2024 · We highlight how gene expression studies have identified molecular signatures for radial glial cell populations and outline what has been learned about the mechanisms underlying the characteristic mode of division observed in outer radial glia cells, mitotic somal translocation.
WebIn addition, we show that PTPRZ1 mediates both mitotic somal translocation and glioblastoma tumor invasion. These data suggest that the presence of heterogeneous GSCs may underlie glioblastoma’s rapid progression and invasion. Summary Glioblastoma is a devastating form of brain cancer.
Web1 feb. 2024 · 2024. TLDR. This work shows that in both human brain organoids and mouse embryos ZEB2 is expressed in telencephalic neuroepithelial cells (NECs) before … show my homrewWeb20 jul. 2024 · Here, we identify EGFR-expressing “Pre-OPCs” that originate from outer radial glial cells (oRGs) and undergo mitotic somal translocation (MST) during division. oRG … show my homework supportWeb25 mrt. 2010 · Mitotic somal translocation distances were measured using Imaris. Only mitotic cells that had long basal processes and no apical ones were considered as oRG … show my homworckWeb12 dec. 2016 · Search life-sciences literature (Over 40 million articles, preprints and more) show my house by satelliteWeb1 jun. 2014 · Basal progenitors (BPs), which comprise basal radial glia (bRG) and basal intermediate progenitors (bIPs), are defined by mitosis occurring at an abventricular location and the absence of ventricular contact. bRG subtypes (see Box 2 for more information) are also shown: proliferative bIP, blue; neurogenic bIP, green. show my houseWeb13 aug. 2024 · e Quantification of hmRG mitotic somal translocation distances (n = 48 cells) in mice. f The GFP expressing hmRG ( n = 6 independent experiments) produced both the daughter neurons that were TUJ1 ... show my house on google mapWeb5 feb. 2024 · Since Lzts1 has inhibitory effect on the microtubule assembly ( Ishii et al., 2001 ), low-level Lzts1 in mitotic aRGs may perturb the formation of astral microtubules and inhibit the astral microtubule–LGN–AJ interaction, which may induce oblique division ( Kawaue et al., 2024) ( Figure 2A ). show my house from street