WebApr 10, 2024 · HIGHLIGHTS. who: Filamentous Fungi and collaborators from the National Cheng Kung University, Taiwan have published the research work: Transcriptional Activation of Biosynthetic Gene Clusters in Filamentous Fungi, in the Journal: (JOURNAL) how: This Tet-On system was applied with A. fumigatus for inducible expression of the gene of … WebThe phosphopantetheine-attachment site (ACP4: S46 and ACP3a: S62) is highlighted with an asterisk. ... The KR-binding epitope of the ACP domain encompasses key residues situated on H I and H II, and combined with previous observations, 17 the ACP domain docks at the same KR C subdomain site in both cis- and trans-AT systems.
PDB 5mso structure summary ‹ Protein Data Bank in Europe …
WebJul 21, 2024 · The phosphopantetheine-binding domain (PP-binding superfamily), conserved in ACP proteins, is the prosthetic group of ACP, which acts as a linker for the attachment of the activated FA and amino acid groups via a phosphodiester bond (Crawford et al. 2008; Meier et al. 2010; ... WebFeb 20, 2024 · Acyl carrier protein (ACP) domains act as interaction hubs within modular polyketide synthase (PKS) systems, employing specific protein-protein interactions to present acyl substrates to a... on my momma bro these birds petty as hell
Functions: acpP, Pseudomonas aeruginosa PAO1
WebPhosphopantetheine tethering is a posttranslational modification that takes place on the active site serine of carrier proteins 138 – ‘acyl carrier proteins (ACPs) and peptidyl carrier proteins (PCPs), also termed thiolation (T) domains’ – during the biosynthesis of fatty … Hei Sook Sul, ... Li Chen, in Progress in Nucleic Acid Research and Molecular … WebFeb 17, 2016 · This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. automatic annotation. Catalytic activity (2E) ... … WebIts crystal structure contains five catalytic domains, two nonenzymatic domains and a shuttle protein domain. Overexpression in FAS can be linked to development of cancer cells (1). Activity of fatty acid synthase (FAS) in mammals is often low in most body tissue. on my mind song jorja smith